Our unique AI-enabled process designs innovative NCEs
targeting any class of protein
at unprecedented speed.
ACCELERATING DRUG DISCOVERY… TRULY.

WHAT WE DO

Target of Interest

1 – TID

Target Identification

  • Identify and validate structural proteins
  • Characterize target druggability through in silico and experimental data

2 – M2H

MolecuLern TO HIT

  • Match targets with MolecuLern
    real data

3 – HV

HIT VALIDATION

  • Validate binding pocket and property enumeration

4 – H2L

HIT TO LEAD

  • Iterative screening, Med-Chem tractability, and lead identification

5 – LO

LEAD OPTIMIZATION

  • NCEs to synthesis
  • SAR to lead selection

6 – CN

Candidate Nomination

  • ADME-Tox
  • Efficacy
  • Developability
  • Pre-formulation
Target of Interest
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Precise: Our training set of real empirical/wet lab data allows us to cover the spectrum of protein/small molecule interactions to discover targetable hot spots, minimizing the “hit-and-miss” of traditional drug discovery.

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Accelerated: Cutting-edge process supported by decades of work and over 5 years of AI/ML development to discover new medicines with previously impossible speed and accuracy.

    
Target Icon

Validated: MolecuLern is trained on hundreds of 3D structures, from PDB and DeepMind AlphaFold protein targets, screened against our IP rich proprietary fragment and NCE library.

Moleculern Driven Pipeline

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Small Molecule Assets Available for Licensing

INTEGRATED DRUG DISCOVERY PROCESS

 

 

 

 

 

 

 

 

PIPELINE PARTNERSHIPS

Biolexis utilizes the MolecuLern process to discover and develop our own NCEs. Our pipeline projects are available for licensing or partnering.

NCE DISCOVERY AND DEVELOPMENT

MolecuLern can discover and develop innovative, IP-rich NCEs targeting any class of proteins. Our training set of real empirical/wet lab data allows us to cover the spectrum of protein/small molecule interactions and discover targetable hot spots on target proteins. MolecuLern takes you from simple concept to drugable NCEs in a fraction of the time. 

Contact Us

CORPORATE HEADQUARTERS
858 S Auto Mall Dr. #102
American Fork, UT 84003
United States

Ph: 801-692-3655   info@biolexistx.com