FIELDS™

Our AI/ML platform designs innovative NCEs
targeting any class of protein
at unprecedented speed.

FIELDS™: ACCELERATING DRUG DISCOVERY

What We Do

Target of Interest

1 – TID

Target Identification

  • Identify and validate structural proteins
  • Characterize target druggability through in silico and experimental data

2 – F2H

FIELDS TO HIT

  • Match targets with FIELDS real data

3 – HV

HIT VALIDATION

  • Validate binding pocket and property enumeration

4 – H2L

HIT TO LEAD

  • Iterative screening, Med-Chem tractability, and lead identification

5 – LO

LEAD OPTIMIZATION

  • NCEs to synthesis
  • SAR to lead selection

6 – CN

Candidate Nomination

  • ADME-Tox
  • Efficacy
  • Developability
  • Pre-formulation
Target of Interest
Target Icon

Precise: Our training set of real empirical/wet lab data allows us to cover the spectrum of protein/small molecule interactions to discover targetable hot spots, minimizing the “hit-and-miss” of traditional drug discovery.

Target Icon

Accelerated: Cutting-edge platform supported by decades of work and over 5 years of AI/ML development to discover new medicines with previously impossible speed and accuracy.

    
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Validated: FIELDS™ is trained on hundreds of 3D structures, from PDB and DeepMind AlphaFold protein targets, screened against our IP rich proprietary fragment and NCE library.

Pipeline

ONCOLOGY

CDK9

Neuroendocrine Prostate
mCRPC
Other Solid Tumors
Leukemias
IPF (D0D Funded)

Q3 2023

Q4 2023

PIM1

Multiple Myeloma
Fibrotic Disorders

Q4 2023

Q1 2024

CNS

HDAC6

Neurodegenerative
Diseases – ALS/AD

Q1 2024

Q1 2025

SERVICES

 

 

 

 

 

 

 

 

PIPELINE PARTNERSHIPS

Biolexis utilizes the FIELDS™ platform to discover and develop our own NCEs. Our pipeline projects are available for licensing or partnering.

NCE DISCOVERY AND DEVELOPMENT

FIELDS™ can discover and develop innovative, IP-rich NCEs targeting any class of proteins. Our training set of real empirical/wet lab data allows us to cover the spectrum of protein/small molecule interactions and discover targetable hot spots on target proteins. FIELDS™ takes you from simple concept to drugable NCEs in a fraction of the time. 

FIELDS™ CHALLENGE

Give us your most challenging protein target and we'll show you what FIELDS™ can do.

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